Hi @NHViet,
We have many WooCommerce websites made in Cwicly, so I can definitively say it can be effectively used.
There are certain things you can style with global styles and some things you may want to use stylesheets to style (such as My Account pages), and depending on the functional and design requirements and any third-party plugins you are using, you may need to choose between the legacy or block based cart and checkout templates.
Generally though, we have had no major obstacles using Cwicly for WooCommerce sites and some of them have been highly customised.